Acute toxicity of 353-nonylphenol and its metabolites for zebrafish embryos
نویسندگان
چکیده
منابع مشابه
Developmental toxicity of nonylphenol in zebrafish (Danio rerio) embryos
Present study reports the response of zebrafish embryos exposed in vivo to graded concentrations of Nonylphenol (NP), ranging from high lethal levels to lower, more environmentally relevant levels. Embryos treated with NP showing developmental abnormalities and morphological alterations in a dose-dependent pattern. Results suggest that early exposure to NP can cause direct and delayed mortaliti...
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Using twenty chemicals commercially available or provided by NCI, we demonstrated the feasibility of using zebrafish embryos to study toxicity response by assessing Median Lethal Concentration (LC50), developmental teratogenicity, and specific liver and kidney toxicity. For the twenty compounds used to study LC50 and liver and kidney toxicity in zebrafish embryos, we found good correlation with...
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Surface disinfection of fertilized fish eggs is widely used in aquaculture to reduce extraovum pathogens that may be released from brood fish during spawning, and this is routinely used in zebrafish Danio rerio research laboratories. Most laboratories use approximately 25 to 50 ppm unbuffered chlorine solution for 5 to 10 min. Treatment of embryos with chlorine has significant germicidal effect...
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Acute toxicity of 4-nonylphenol (NP) was examined in six freshwater species from three phyla - platyhelminthes, arthropoda and mollusca. Values of the 48-hour LC(50) of NP for six species ranged from 20 to 508 ug/L and values of the 96-hour LC(50) for four species ranged from 120 to 457 ug/L. The most sensitive species tested was a water flea, Ceriodaphnia cornuta, with a 48-hour LC(50) of 20 m...
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Silver nanoparticles cause toxicity in exposed organisms and are an environmental health concern. The mechanisms of silver nanoparticle toxicity, however, remain unclear. We examined the effects of exposure to silver in nano-, bulk-, and ionic forms on zebrafish embryos (Danio rerio) using a Next Generation Sequencing approach in an Illumina platform (High-Throughput SuperSAGE). Significant alt...
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ژورنال
عنوان ژورنال: Environmental Science and Pollution Research
سال: 2009
ISSN: 0944-1344,1614-7499
DOI: 10.1007/s11356-009-0123-7